Lucy Grymes (1743-1830) was a member of a prominent Revolutionary-era family and the spouse of Thomas Nelson Jr. Thomas Nelson Jr was a public official and military officer whose career or family position supplies an important part of this entry’s Revolutionary context. The marriage connected Lucy Grymes to the political, military, commercial, or social developments surrounding the Revolution. This life overlapped the Revolutionary era, when war, political upheaval, disrupted trade, military service, and changing governments placed unusual demands on households and extended families. Surviving documentation is strongest in genealogical, family, estate, and marriage records rather than in a separate public biography. Including Lucy Grymes in HistoryGPS recognizes that households, marriages, property, correspondence, hospitality, and kinship networks were essential parts of the world in which Revolutionary leaders acted.