Isham Randolph of Dungeness was a sea captain and planter who represented Goochland County in the Virginia House of Burgesses from 1738 to 1741. He represented Goochland County in the House of Burgesses from 1738 to 1741. He also acted as a Virginia correspondent of the London merchant Peter Collinson. In 1738, Randolph succeeded Abraham Nicholas as the adjutant general of Virginia. Randolph died in November 1742 and was buried on Turkey Island. In his will he assigned guardians of his children, including his son-in-law, Peter Jefferson (the father of President Thomas Jefferson.) His nephew William Randolph III would succeed him in the House of Burgesses but serve only one session (with his cousin of the same name representing Charles City County downstream). The available biographical account does not describe a continuous final medical course. It gives no dependable sequence of treatment and last symptoms from which to reconstruct a more detailed bedside narrative.